Chinese Academy of SciencesShanghai Institutes, Shanghai, P. R. China

Group Members

Researchers:

Sen. Eng. Wenping Xu, Dr. Yang Zhang,

mechanism and metabolism of action of pesticides, focused on the potential target of pesticides and its effects on non-target organisms and environmental ecology.

Professional experience

2010-now     East China University of Science and Technology (ECUST)

1987-2010     Shanghai Pesticide Research Institute

1996-1997     Agricultural of bioactive substance BASF of Germany

1991-1992     Agricultural of bioactive substance in RIKEN of Japan

1982-1984     Wuhan Institute of Hydrobiology, Chinese Academy of Science

Publication from 2010 in ECUST:

1. Yun Yang, Jufang Gao, Yang Zhang, Wenping Xu, Youwu Hao, Zhiping Xu, Liming Tao*.,Natural pyrethrins induce autophagy of HepG2 cells through the activation of AMPK/mTOR pathway. Environmental Pollution, 2018, 241:1091-1097.

2. Yun Yang, Wenjing Liu, Jian Wang, Yang Zhang, Wenping Xu, Liming Tao*.,The different effects of natural pyrethrins and beta -cypermethrin on human hepatocyte QSG7701 cells by ROS-mediated oxidative damage. Environmental Science & Pollution Research International (2018),https://doi.org/10.1007/s11356-018-2503-3.

3. Yang Zhang, Yuansen Chang, Haijing Cao, Wenping Xu, Zhong Li, Liming Tao*., Potential threat of Chlorpyrifos to human liver cells via the caspase-dependent mitochondrial pathways. Food & Agricultural Immunology,2018, 29:294-305.

4. Wenping Xu, Songlin Liu, Yang Zhang, Jufang Gao, Mingjun Yang, Xiao  Liu, Liming Tao*., Cypermethrin resistance conferred by increased target insensitivity and metabolic detoxification in Culex pipiens pallens Coq. Pesticide Biochemistry and Physiology, 2017, 142:77.

5. Yang Zhang, Jigang Wu, Wenping Xu, Jufang Gao, Haijing Cao, Mingjun  Yang, Bo Wang, Youwu Hao, Liming Tao*., Cytotoxic effects of Avermectin on human HepG2 cells in vitro bioassays. Environmental Pollution, 2017, 220(Pt B):1127-1137.

6. Yun Yang, Mimi Zong, Wenping Xu, Yang  Zhang, Bo Wang, Mingjun Yang,  Liming Tao*., Natural pyrethrins induces apoptosis in human hepatocyte cells via Bax- and Bcl-2-mediated mitochondrial pathway. Chemico-Biological Interactions, 2017, 262:38-45.

7. Wenping Xu, Bo Wang, Mingjun Yang, Yang Zhang, Zhiping Xu, Yun Yang,  Haijing Cao, Liming Tao*., Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells. Environmental Toxicology and Pharmacology, 2017, 49:89 - 96.

8. Youwu Hao, Gaohui Zhou, Wei Wu, Yang Zhang, Liming  Tao, Jianhua Yao, Wenping Xu*., Synthesis and antiviral evaluation of novel N-6 substituted adenosine analogues. Tetrahedron Letters, 2017, 58(3):190-193.

9. Mingjun Yang, Bo Wang, Jufang Gao, Yang Zhang, Wenping Xu,  Liming Tao*., Spinosad induces programmed cell death involves mitochondrial dysfunction and cytochrome c release in spodoptera frugiperda Sf9 cells. Chemosphere, 2017, 169:155-161.

10. Mingjun Yang, Guanggang Xiang, Diqiu Li, Yang Zhang, Wenping Xu,  Liming Tao*., The insecticide spinosad induces DNA damage and apoptosis in HEK293 and HepG2 cells. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2016, 812:12-19.

11. Yang Zhang, Mingming Luo, Wenping Xu, Mingjun Yang, Bo Wang, Jufang  Gao, Yaxiao Li, and Liming Tao*., Avermectin Confers Its Cytotoxic Effects by Inducing DNA Damage and Mitochondria-Associated Apoptosis. Journal of Agricultural and Food Chemistry, 2016, 64(36): 6895-6902.

12. Zhiping Xu, Miaoqing Lu, Mingjun Yang, Wenping Xu, Jufang Gao, Yang  Zhang, Yun Yang, Liming Tao*., Pyrethrum-extract induced autophagy in Insect cells: A new target? Pesticide Biochemistry and Physiology, 2016, 137:21-26

13. Xiaoqin Yu, Yang Zhang, Mingjun Yang, Junfu Guo, Wenping Xu, Jufang  Gao, Yaxiao Li, Liming Tao*., Cytotoxic effects of tebufenozide in vitro bioassays. Ecotoxicology and Environmental Safety, 2016, 129: 180-188.

14. Yang Zhang, Songlin Liu, Xing Yang, Mingjun Yang, Wenping Xu, Yaxiao  Li, Liming Tao*., Staurosporine shows insecticidal activity  against Mythimna separata．Pesticide Biochemistry and Physiology, 2016, 128: 37-44.

15. Xiwei Wu, Lei Zhang, Chao Yang, Mimi Zong, Qingchun Huang*,  Liming Tao., Detection on emamectin benzoate induced apoptosis and DNA damage in  Spodoptera rugiperda Sf9 cell line.  Pesticide Biochemistry and Physiology, 2016, 126: 6–12.

16. Diqiu Li, Qingchun Huang*,  Miaoqing Lu, Lei Zhang, Zhichuan Yang, Mimi Zong, Liming  Tao*., The organophosphate insecticide chlorpyrifos confers its genotoxic effects by inducing DNA damage and cell apoptosis.  Chemosphere，2015, 135: 387–393.

17. Diqiu Li, Xiwei Wu, Xiaoqin Yu, Qingchun Huang, Liming  Tao*., Synergistic effect of nonionic surfactants Tween 80 and PEG6000 on cytotoxicity of insecticides. Environmental Toxicology and Pharmacology, 2015, 39: 677–682.

18. Qingchun Huang*, Xiwei Wu, Xiaoqin Yu, Lei Zhang, Miaoqing Lu,  Liming Tao*., Comparison of the cytotoxic impact of chlorfluazuron on selected insect and human cell lines.  Environmental Toxicology Chemical, 2015, 34(7): 1675-1682.

19. Wenping Xu, Qingchun Huang*, Xiwei Wu, Xiaoqin Yu, Xuexiao  Wang, Liming Tao. Property of midgut a-amylase from Mythimna separate (Lepidoptera: Noctuidae) larvae and its responses to potential inhibitors in vitro. Journal of Insect Science, 2014, 14(1).

20. Xiuyuan Zhuang, Daojing Zhang, Wen Qin, Jia Deng, Hui Shan,  Liming Tao* and Yuanguang Li*., A comparison on the preparation of hot water extracts from Chlorella pyrenoidosa (CPEs) and radical scavenging and macrophage activation effects of CPEs. Food & Function,2014, 5(12):3252-3260.

21. Xiang Guanggang, Li Diqiu, Yuan Jianzhong, Guan Jingmin, Zhai  Huifeng, Shi Mingan*, Tao Liming*., Carbamate insecticide methomyl confers cytotoxicity through DNA damage induction.  Food and Chemical Toxicology,2013, 53,352-358.

22. Wenping Xu, Daojing Zhang, Congcong Si, Liming  Tao*., ANTIFUNGAL MACROLIDES FROM Streptomyces cavourensis YY01-17. Chemistry of Natural Compounds, 2013, 49(5), 988-989.

23. Daojing Zhang, Gang Wei, Ying Wang, Congcong Si, Li Tian,  Li-ming Tao* and Yuan-guang Li. Bafilomycin K, a new antifungal macrolide from Streptomyces flavotricini Y12-26. The Journal of Antibiotics, 2011, 64, 391–393.

24. Baoju Li, Huizhu Yuan, Jichao Fang, Liming  Tao, Qingchun Huang*, Xuhong Qian*, Zhijin Fan. Recent progress of highly efficient in vivo biological screening for novel agrochemicals in China. Pest Management Science,2010, 66 (3): 229 – 344

25. Dao-Jing Zhang, Rong-Feng Liu, Yuan-Guang Li*, Li-Ming  Tao, Li Tian. Two New Antifungal Cyclic Lipopeptides from Bacillus marinus B-9987. Chemical & Pharmaceutical Bulletin, 2010, 58(12):1630-1634

26. Rong-Feng Liu, Dao-Jing Zhang, Yuan-Guang Li*, Li-Ming  Tao, Li Tian*. A New Antifungal Cyclic Lipopeptides from Bacillus marinus B-9987. Helvetica Chimica Acta, 2010, 93 (12): 2419-2425.